Ross and Rachel – Friends
After a whirlwind romance, Ross and Rachel’s breakup over his infamous "we were on a break" moment left fans heartbroken, marking one of the most iconic splits in TV history.
– Meredith and Derek – Grey’s Anatomy
Meredith and Derek faced many ups and downs, but their temporary breakup before ultimately reuniting was a gut-wrenching moment in a relationship defined by tragedy and hope.
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– Jim and Pam – The Office (Brief Separation)
Although Jim and Pam’s relationship was mostly solid, their brief emotional distance during Jim’s time in Philadelphia was heartbreaking for fans invested in their love story.
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Carrie and Aidan – Sex and the City
Carrie’s breakup with Aidan, who was ready for marriage but Carrie wasn’t, left viewers devastated, as many believed Aidan was the perfect match for her.
Chuck and Blair – Gossip Girl
The power couple’s on-again, off-again relationship was full of dramatic twists, but their breakup after Chuck’s betrayal left fans emotionally shattered.
– Buffy and Angel – Buffy the Vampire Slayer
Buffy and Angel’s love was doomed from the start, but their breakup, driven by Angel’s decision to leave to protect Buffy, was a tear-jerking moment for viewers.
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Luke and Lorelai – Gilmore Girls
After years of will-they-won’t-they tension, Luke and Lorelai’s breakup over communication issues and postponed marriage plans left fans heartbroken.
Don and Betty – Mad Men
Don and Betty’s marriage was fraught with problems, but their eventual divorce was a sad and inevitable moment, marking the end of their troubled relationship.